Guidance: Clinical platform trials for coronavirus (COVID-19) treatments

Past and current clinical trials into therapeutic and antiviral treatments for COVID-19, how to take part, and which treatments have proven to be effective.

About clinical trials

Clinical trials are essential to finding new and improved methods of treating different diseases including coronavirus (COVID-19).

Clinical trials allow us to understand whether new treatments:

  • genuinely improve recovery and survival for patients who contract COVID-19
  • should be made available more widely in the NHS

Phase 1 and 2 trials

Phase 1 and 2 trials are early-stage trials involving small numbers of participants to ensure a treatment is safe to use and shows evidence of a benefit beyond the standard of care.

Treatments that are found to be safe at this stage may then proceed to be tested in a phase 3 clinical trial.

Phase 3 trials

Phase 3 trials involve large numbers of patients and assess whether a treatment is effective enough to be used more widely in the NHS.

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Author: HM Government
Date published: 12/10/2022